#Study of gems full

Participants classified as reaching dementia end point were then referred for a full neurological evaluation and a magnetic resonance imaging (MRI) scan at the clinical site to confirm that the participants met clinical criteria for dementia, assess for atypical causes of dementia and assign a specific dementia classification. Results from the neuropsychological battery and the clinical assessments were reviewed by an expert panel blinded to treatment assignment. Medical records from all overnight hospitalizations and all fatal events were collected in the field centers. The full neuropsychological battery included tests on memory, construction, language, psychomotor speed, attention, executive functions and global cognitive function.Ĭlinical assessments were also performed including physical examination, ECG, vital signs, blood pressure, pulse, activities of daily living, functional assessment, health habits, information on current medications, adherence check, adverse events and interval medical history. Participants were also administered the full battery if the participant or family reported the onset of a new memory or other cognitive problem, or if in the intervening six months there was a diagnosis of dementia by a private physician, or the participant initiated a medication for a memory or cognitive problem. Failure to pass 2 of 3 of these tests required a repeat administration of the full neuropsychological battery. By following our gemmology pathway or diamond pathway and successfully completing our courses, Graduates are eligible to apply to join the Association and become FGA or DGA Members. There are two routes to follow: Gemmology or Diamonds. The participants had to pass 2 out of 3 of the preliminary battery scales: the 3MSE, the Clinical Dementia Rating (CDR) or the Alzheimer's Disease Assessment Scale (ADAS). Gem-A offers internationally recognised qualifications in gemmology and diamond studies. The participants were assessed every 6 months.Īt each visit, the Informant Questionnaire for Cognitive Decline in the Elderly was completed by a proxy. Demographic characteristics were assessed using questionnaires including age, sex, race and years of education. The evaluation included: physical examination, neurological examination, ECG, vital signs, blood pressure, symptoms and health habits questionnaire, functional assessment and information on current medication. Recruitment and screening were done in 3 phases with cognitive, medical and other exclusion criteria performed at each stage.ĭuring a telephone interview, self-reported medical history and the Telephone Interview for Cognitive Assessment were used to screen potential participants.Īt the screening visit, participants completed a cognitive screener (Modified Mini Mental State Examination (3MSE) and Dementia Questionnaire (DQ) completed by a proxy) followed by neuropsychological testing (estimated verbal IQ, memory, construction, language, psychomotor speed, attention, executive functions and global cognitive function), phlebotomy and other functional assessment necessary to determine eligibility for study inclusion.Īt the baseline visit, a final evaluation of eligibility and randomization were done.

Study of gems